/ Dictionary / Index L Last Supper: Meaning and Definition of Find definitions for: Last' Sup'per Pronunciation: [key] the supper of Jesus and His disciples on the eve of His Crucifixion. Cf. Lord's Supper (def. 1). a work of art representing this. (italics.)The, a mural (1495–98) by Leonardo da Vinci. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. last straw Last Things Related Content Daily Word Quiz: careening Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language