/ Dictionary / Index A alkylation: Meaning and Definition of Find definitions for: al•kyl•a•tion Pronunciation: (al"ku-lā'shun), [key] — n. Chem. the replacement of a hydrogen atom in an organic compound by an alkyl group. the addition of a paraffin to an olefin, done in the manufacture of gasoline. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. alkylating drug alkyl group Related Content Daily Word Quiz: loquacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language