/ Dictionary / Index A annihilate: Meaning and Definition of Find definitions for: an•ni•hi•late Pronunciation: (u-nī'u-lāt"), [key] — -lat•ed, -lat•ing. to reduce to utter ruin or nonexistence; destroy utterly: The heavy bombing almost annihilated the city. to destroy the collective existence or main body of; wipe out: to annihilate an army. to annul; make void: to annihilate a law. to cancel the effect of; nullify. to defeat completely; vanquish: Our basketball team annihilated the visiting team. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: annihilate (Thesaurus) annihilable annihilation Related Content Daily Word Quiz: gregarious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language