/ Dictionary / Index A antihistamine: Meaning and Definition of Find definitions for: an•ti•his•ta•mine Pronunciation: (an"ti-his'tu-mēn", -min), [key] — n. Biochem., Pharm. any of certain compounds or medicines that neutralize or inhibit the effect of histamine in the body, used chiefly in the treatment of allergic disorders and colds. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: antihistamine (Thesaurus) antiheroine antihistaminic Related Content Daily Word Quiz: mamba Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language