/ Dictionary / Index A arteriosclerosis: Meaning and Definition of Find definitions for: ar•te•ri•o•scle•ro•sis Pronunciation: (är-tēr"ē-ō-sklu-rō'sis), [key] — n. degenerative changes in the arteries, characterized by thickening of the vessel walls and accumulation of calcium with consequent loss of elasticity and lessened blood flow. Cf. atherosclerosis. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: arteriosclerosis (Thesaurus) arteriole arteriotomy Related Content Daily Word Quiz: cautious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language