/ Dictionary / Index B base-pairing rules: Meaning and Definition of Find definitions for: base'-pair•ing rules" Pronunciation: [key] — Genetics. Genetics. constraints imposed by the molecular structure of DNA and RNA on the formation of hydrogen bonds among the four purine and pyrimidine bases such that adenine pairs with thymine or uracil, and guanine pairs with cytosine. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. base-pairing base path Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language