/ Dictionary / Index B buffy coat: Meaning and Definition of Find definitions for: buff'y coat" Pronunciation: [key] — Biochem. Biochem. a yellowish-white layer consisting of leukocytes that, upon centrifugation of blood, covers the red blood cells. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. buffy bufotenine Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language