/ Dictionary / Index C cardinal sign: Meaning and Definition of Find definitions for: car'dinal sign' Pronunciation: [key] — Astrol. Astrol. any of the four astrological signs, Aries, Cancer, Libra, or Capricorn, that begin at the equinoxes and solstices, thus marking the beginning of the seasons: characterized by the attribute of strong initiative. Cf. quadruplicity. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. cardinal points cardinal system Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language