/ Dictionary / Index C chalone: Meaning and Definition of Find definitions for: chal•one Pronunciation: (kal'ōn), [key] — n. Physiol. an endocrine secretion that depresses or inhibits physiological activity. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Chalmers Châlons Related Content Daily Word Quiz: lunar Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language