/ Dictionary / Index C chamber of commerce: Meaning and Definition of Find definitions for: cham'ber of com'merce Pronunciation: [key] an association, primarily of people in business, to promote the commercial interests of an area. Abbr.: C of C Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. chamber music chamber of deputies Related Content Daily Word Quiz: arboreal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language