/ Dictionary / Index C chancre: Meaning and Definition of Find definitions for: chan•cre Pronunciation: (shang'kur), [key] — n. Pathol. the initial lesion of syphilis and certain other infectious diseases, commonly a more or less distinct ulcer or sore with a hard base. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: chancre (Thesaurus) Chan Chan chancroid Related Content Daily Word Quiz: belligerent Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language