/ Dictionary / Index C cheerio: Meaning and Definition of Find definitions for: cheer•i•o Pronunciation: (chēr'ē-ō", chēr"ē-ō'), [key] — interj., n., pl. cheer•i•os. —interj. good-bye; good-bye and good luck. (used as a toast to one's drinking companions.) —n. a good-bye or farewell. a toast of “cheerio!” Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: cheerio (Thesaurus) cheerful cheerlead Related Content Daily Word Quiz: immense Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language