/ Dictionary / Index C Chicago Fire: Meaning and Definition of Find definitions for: Chica'go Fire' Pronunciation: [key] — U.S. Hist. U.S. Hist. a three-day fire in Chicago, Ill., in 1871 that largely destroyed the city and took several hundred lives. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Chicago Board of Trade Chicago Heights Related Content Daily Word Quiz: eureka Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language