/ Dictionary / Index C Christmas disease: Meaning and Definition of Find definitions for: Christ'mas disease" Pronunciation: [key] — Pathol. Pathol. a hereditary disease characterized by an inability of the blood to clot because of a deficiency of a coagulation factor. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Christmas club Christmas Eve Related Content Daily Word Quiz: dentifrice Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language