/ Dictionary / Index C chromosomal aberration: Meaning and Definition of Find definitions for: chromoso'mal aberra'tion Pronunciation: [key] — Genetics. Genetics. any irregularity or abnormality of chromosome distribution, number, structure, or arrangement. Cf. deletion, duplication, inversion, translocation. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. chromoprotein chromosome Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language