/ Dictionary / Index C Colorado Desert: Meaning and Definition of Find definitions for: Col'orad'o Des'ert Pronunciation: [key] an arid region in SE California, W of the Colorado River. ab. 2500 sq. mi. (6475 sq. km). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Colorado blue spruce coloradoite Related Content Daily Word Quiz: lunar Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language