/ Dictionary / Index C colostomy: Meaning and Definition of Find definitions for: co•los•to•my Pronunciation: (ku-los'tu-mē), [key] — pl. -mies. the construction of an artificial opening from the colon through the abdominal wall, thus bypassing a diseased portion of the lower intestine and permitting the passage of intestinal contents. the opening so constructed. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: colostomy (Thesaurus) Colossus of Memnon colostrum Related Content Daily Word Quiz: pristine Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language