/ Dictionary / Index C Cuffe: Meaning and Definition of Find definitions for: Cuf•fe Pronunciation: (kuf'ē), [key] 1759–1817, U.S. merchant, seaman, and philanthropist: advocated U.S. black emigration to Africa. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. cuff button Cuffee Related Content Daily Word Quiz: reiterate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language