/ Dictionary / Index D defederalize: Meaning and Definition of Find definitions for: de•fed•er•al•ize Pronunciation: (dē-fed'ur-u-līz"), [key] — -ized, -iz•ing. to shift the functions or powers of (an agency, service, etc.) from the jurisdiction of the federal government to that of state or local government: to defederalize construction loans. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. defector defence Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language