/ Dictionary / Index D defense mechanism: Meaning and Definition of Find definitions for: defense' mech"anism Pronunciation: [key] the defensive reaction of an organism, as against a pathogenic microorganism. an unconscious process, as denial, that protects an individual from unacceptable or painful ideas or impulses. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. defenseman defensible Related Content Daily Word Quiz: nonchalant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language