/ Dictionary / Index D demyelinate: Meaning and Definition of Find definitions for: de•my•e•li•nate Pronunciation: (di-mī'u-lu-nāt"), [key] — -nat•ed, -nat•ing. to obliterate or remove the myelin sheath from (a nerve or nerves). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: demyelinate (Thesaurus) demy demyelination Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language