/ Dictionary / Index D denature: Meaning and Definition of Find definitions for: de•na•ture Pronunciation: (dē-nā'chur), [key] — -tured, -tur•ing. to deprive (something) of its natural character, properties, etc. to render (any of various alcohols) unfit for drinking by adding an unwholesome substance that does not alter usefulness for other purposes. to treat (a protein or the like) by chemical or physical means so as to alter its original state. to make (fissionable material) unsuitable for use in an atomic weapon by mixing it with unfissionable material. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: denature (Thesaurus) denaturalize denatured alcohol Related Content Daily Word Quiz: clairvoyant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language