/ Dictionary / Index D Depew: Meaning and Definition of Find definitions for: De•pew Pronunciation: (du-py'), [key] — n. 1834–1928, U.S. lawyer, legislator, and orator. a town in W New York. 19,819. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. depersonalize dephosphorylate Related Content Daily Word Quiz: ounterfeit Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language