/ Dictionary / Index D depopulate: Meaning and Definition of Find definitions for: de•pop•u•late Pronunciation: (v.dē-pop'yu-lāt"adj.dē-pop'yu-lit, -lāt"), [key] — v., adj. -lat•ed, -lat•ing, —v.t. to remove or reduce the population of, as by destruction or expulsion. —adj. depopulated. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: depopulate (Thesaurus) Depo-Provera deport Related Content Daily Word Quiz: agitated Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language