/ Dictionary / Index D desipramine: Meaning and Definition of Find definitions for: de•si•pra•mine Pronunciation: (du-zip'ru-mēn", dez"u-pram'in), [key] — n. Pharm. a tricyclic antidepressant, CHN, used for symptomatic relief in a variety of depressive states. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: desipramine (Thesaurus) desinence desirable Related Content Daily Word Quiz: philtrum Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language