/ Dictionary / Index D Des Moines: Meaning and Definition of Find definitions for: Des Moines Pronunciation: (du moin'), [key] a city in and the capital of Iowa, in the central part, on the Des Moines River. 191,003. a river flowing SE from SW Minnesota through Iowa to the Mississippi River. ab. 530 mi. (850 km) long. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. desmoid Desmond Related Content Daily Word Quiz: dissonant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language