/ Dictionary / Index D desolation: Meaning and Definition of Find definitions for: des•o•la•tion Pronunciation: (des"u-lā'shun), [key] — n. an act or instance of desolating. the state of being desolated. devastation; ruin. depopulation. dreariness; barrenness. deprivation of companionship; loneliness. sorrow; grief; woe. a desolate place. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: desolation (Thesaurus) desolate desorb Related Content Daily Word Quiz: morose Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language