/ Dictionary / Index D desperation: Meaning and Definition of Find definitions for: des•per•a•tion Pronunciation: (des"pu-rā'shun), [key] — n. the state of being desperate or of having the recklessness of despair. the act or fact of despairing; despair. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: desperation (Thesaurus) desperate despicable Related Content Daily Word Quiz: soporific Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language