/ Dictionary / Index D desquamate: Meaning and Definition of Find definitions for: des•qua•mate Pronunciation: (des'kwu-māt"), [key] — -mat•ed, -mat•ing. to come off in scales, as the skin in certain diseases; peel off. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: desquamate (Thesaurus) Des Prés D. ès S. Related Content Daily Word Quiz: nonchalant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language