/ Dictionary / Index D disaffect: Meaning and Definition of Find definitions for: dis•af•fect Pronunciation: (dis"u fekt'), [key] — v.t. to alienate the affection, sympathy, or support of; make discontented or disloyal: The dictator's policies had soon disaffected the people. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: disaffect (Thesaurus) disadvantageous disaffected Related Content Daily Word Quiz: eureka Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language