/ Dictionary / Index D downer: Meaning and Definition of Find definitions for: down•er Pronunciation: (dou'nur), [key] — n. a depressant or sedative drug, esp. a barbiturate. a depressing experience, person, or situation. an old or diseased animal, esp. one that cannot stand up. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: downer (Thesaurus) down-easter Downers Grove Related Content Daily Word Quiz: reclusive Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language