/ Dictionary / Index D downtown: Meaning and Definition of Find definitions for: down•town Pronunciation: (doun'toun'), [key] — adv. to or in the main business section of a city. —adj. of, pertaining to, or situated in the main business section of a city. —n. the main business section of a city. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: downtown (Thesaurus) down-to-earth downtrend Related Content Daily Word Quiz: agitated Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language