/ Dictionary / Index D drug abuse: Meaning and Definition of Find definitions for: drug' abuse" Pronunciation: [key] addiction to drugs. substance abuse involving drugs. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. drug drug addict Related Content Daily Word Quiz: morose Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language