/ Dictionary / Index D drugless: Meaning and Definition of Find definitions for: drug•less Pronunciation: (drug'lis), [key] — adj. being without the use of drugs, as certain methods of medical treatment. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: drugless (Thesaurus) druggy drugmaker Related Content Daily Word Quiz: arid Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language