/ Dictionary / Index D Dubuque: Meaning and Definition of Find definitions for: Du•buque Pronunciation: (du-byk'), [key] — n. a city in E Iowa, on the Mississippi River. 62,321. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: dubuque (Thesaurus) Dubuffet duc* Related Content Daily Word Quiz: nonchalant Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language