/ Dictionary / Index E efficacy: Meaning and Definition of Find definitions for: ef•fi•ca•cy Pronunciation: (ef'i-ku-sē), [key] — pl. -cies. capacity for producing a desired result or effect; effectiveness: a remedy of great efficacy. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: efficacy (Thesaurus) efficacity efficiency Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language