/ Dictionary / Index E eighteen-wheeler: Meaning and Definition of Find definitions for: eight•een-wheel•er Pronunciation: (ā'tēn-hwē'lur, -wē'-), [key] — n. a large tractor-trailer, usually having ten wheels on the cab and eight on the trailer. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Eighteenth Amendment eightfold Related Content Daily Word Quiz: secular Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language