/ Dictionary / Index E empyema: Meaning and Definition of Find definitions for: em•py•e•ma Pronunciation: (em"pē-ē'mu, -pī-), [key] — n. Pathol. a collection of pus in a body cavity, esp. the pleural cavity. Also called Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: empyema (Thesaurus) empurple empyreal Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language