/ Dictionary / Index E epi-: Meaning and Definition of Find definitions for: epi- Pronunciation: [key] a prefix occurring in loanwords from Greek, where it meant “upon,” “on,” “over,” “near,” “at,” “before,” “after” (epicedium; epidermis; epigene; epitome); on this model, used in the formation of new compound words (epicardium; epinephrine). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: epi- (Thesaurus) Ephs. epibenthos Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language