/ Dictionary / Index E Epirus: Meaning and Definition of Find definitions for: E•pi•rus Pronunciation: (i-pī'rus), [key] — n. an ancient district in NW Greece and S Albania. a modern region in NW Greece. 310,344; 3573 sq. mi. (9255 sq. km). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: epirus (Thesaurus) epirogeny Epis. Related Content Daily Word Quiz: endear Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language