/ Dictionary / Index E epistemic: Meaning and Definition of Find definitions for: ep•i•ste•mic Pronunciation: (ep"u-stē'mik, -stem'ik), [key] — adj. of or pertaining to knowledge or the conditions for acquiring it. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: epistemic (Thesaurus) epistaxis epistemology Related Content Daily Word Quiz: stringent Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language