/ Dictionary / Index E E region: Meaning and Definition of Find definitions for: E region Pronunciation: [key] the region of the ionosphere in which the E layer forms. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Erector Set -erel Related Content Daily Word Quiz: frugal Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language