/ Dictionary / Index E estrogen replacement therapy: Meaning and Definition of Find definitions for: es'trogen replace"ment ther"apy Pronunciation: [key] the administration of estrogen, esp. in postmenopausal women, to reduce the chance of osteoporosis and sometimes to lower cholesterol levels. Abbr.: ERT Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. estrogenic estrone Related Content Daily Word Quiz: fabricate Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language