/ Dictionary / Index F first strike: Meaning and Definition of Find definitions for: first' strike' Pronunciation: [key] the initial use of nuclear weapons in a conflict, in which the attacker tries to destroy the adversary's strategic nuclear forces. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. First State first-string Related Content Daily Word Quiz: perspicacious Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language