/ Dictionary / Index F Frankfort on the Main: Meaning and Definition of Find definitions for: Frank'fort on the Main' Pronunciation: (mān), [key] a city in W central Germany, on the Main River. 618,500. Also calledGerman, Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Frankfort Frankfort on the Oder Related Content Daily Word Quiz: fidelity Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language