/ Dictionary / Index G generalissimo: Meaning and Definition of Find definitions for: gen•er•al•is•si•mo Pronunciation: ( jen"ur-u-lis'u-mō"), [key] — pl. -mos. the supreme commander of the armed forces. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: generalissimo (Thesaurus) general headquarters generalist Related Content Daily Word Quiz: endear Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language