/ Dictionary / Index G great-grandniece: Meaning and Definition of Find definitions for: great-grand•niece Pronunciation: (grāt"gran'nēs", -grand'-), [key] — n. a granddaughter of one's nephew or niece. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. great-grandnephew great-grandparent Related Content Daily Word Quiz: paradox Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language