/ Dictionary / Index G gristle: Meaning and Definition of Find definitions for: gris•tle Pronunciation: (gris'ul), [key] — n. cartilage, esp. in meats. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: gristle (Thesaurus) grist gristly Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language