/ Dictionary / Index G guanine: Meaning and Definition of Find definitions for: gua•nine Pronunciation: (gwä'nēn), [key] — n. Biochem. a purine base, CHNO, that is a fundamental constituent of DNA and RNA, in which it forms base pairs with cytosine. Symbol: G&hasp; Cf. guanosine. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: guanine (Thesaurus) guanidine guanine deaminase Related Content Daily Word Quiz: neologism Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language