/ Dictionary / Index G guayule: Meaning and Definition of Find definitions for: gua•yu•le Pronunciation: (gwä-y'lē, wä- Sp. gwä-y'le), [key] — pl. -les a composite shrub, Parthenium argentatum, of the southwestern U.S. and Mexico, yielding a form of rubber. the rubber obtained from this plant. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: guayule (Thesaurus) Guaynabo gubbah Related Content Daily Word Quiz: acquiesce Analogy of the Day: Today’s Analogy Spelling Bee: Today’s Spelling Bee Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language